Miss Spider
Miss Spider is a giant talking female spider and one of the deuteragonists from James and the Giant Peach. She is voiced by Susan Sarandon in the movie.

She is described as decent and friendly in the novel. In the movie adaption, she tends to keep to herself at times. Also in the movie, she and Mr. Centipede are like Dog and Cat, though they show to have feelings for each other. This is shown when Miss Spider kisses Centipede on the cheek which results in him blushing and smiling after the pirate battle. Another example is when the two are dancing together when along with Mr. Grasshopper are singing "Family." Miss Spider has a motherly relationship with James due to James saving her from his aunts.